unique
PRP-PRF-A PRF
therapy

Achieve a lifting effect naturally!

Regenerative medicine uses its own human resources to rejuvenate. One of the most effective is autologous plasma therapy – PRP – therapy – this is the use of blood plasma for restoration, rejuvenation and prevention of aging. Plasma contains valuable and important components capable of repairing, stimulating, reducing inflammation, boosting immunity, supplying nutrients and detoxifying cells and tissues.

PRP is a natural product and 100% biocompatible!

PRP stands for Platelet Rich Plasma. It is extracted from the patient’s own blood by centrifugation.

PRP-therapy is an autotransfusion minimally invasive regenerative method of treatment. PRP is platelet rich plasma which contains 1 to 1.5 million platelets per ml of plasma, which is 5 to 7 times more concentrated than whole blood. Platelets contain the entire spectrum of growth factors. This serum activates the natural reparative abilities of the human body. As a result, PRP therapy stimulates the restoration of the skin and mucous membranes, helps to eliminate signs of aging, improves tone and complexion, and eliminates skin defects.

PRF is platelet-rich fibrin, a bioproduct from the patient’s own blood. PRF is actually a bioactive “patch” derived from one’s own blood that stimulates the healing of wounds or skin imperfections.

Plasma is applied by local injection into the treated area. Platelets together with their growth factors (PDGF AB and BB, IGF, EFG, VEGF, TGF Beta 1 and Beta 2) activate a cascade of anti-inflammatory, regenerative and reparative processes in pathologically altered tissues, especially tendons, cartilage, skin and bones.

Modern treatments are undoubtedly very effective, but the more synthetic products enter our lives, the more we appreciate natural ones. The increase in patients with reduced immunity, allergic reactions, chronic pain syndromes, premature aging and lack of nutrients with sufficient nutrition makes us, doctors, look for simple, effective and safest methods of treatment. And autologous plasma therapy is one of them for several reasons:

  • maximum possible safety, no risk of immunological and allergic reactions
  • blood plasma – the liquid as a part of the blood is involved in all life processes, where there is no blood supply, which means no plasma, there is no life
  • plasma is a unique fantastic cocktail of very valuable and important ingredients that can restore, stimulate, reduce inflammation, increase immunity, supply nutrients and remove toxins from cells and tissues
  • plasma is part of the intercellular mass of connective tissue, and cells cannot live without this substance

We have seen an example of the work of plasma components in tissue healing many times in life: when an incision is made, blood flows, it contains dissolved substances such as fibrinogen, which polymerizes at lightning speed and turns into fibrin and forms a clot that closes the wound. Then the platelets, the blood cells, are activated and secrete substances that immediately begin to repair the damage. Blood plasma proteins immediately turn on, transporting damaged elements and supplying new building materials.

An incision-like reaction can be mimicked by injecting autologous plasma and thereby alerting the body to a problem, a sore joint, bad skin, muscle wasting, non-healing wounds, scars, hair loss.

  • smoothing wrinkles on the forehead in three weeks
  • elimination of wrinkles around the eyes
  • smoothing of nasolabial folds
  • elimination of signs of aging
  • improvement of tone and complexion
  • lifting effect
  • stimulation of the restoration of the skin and mucous membranes
  • elimination of skin defects
  • arthrosis of large joints of the knee, shoulder and hip joints
  • joints of fingers and toes
  • chronic pain in the Achilles tendon
  • diseases of the muscular attachments, such as tennis elbow tennis elbow
  • postoperative inflammation after arthroscopic surgery
  • acne scars
  • small wrinkles
  • stretch marks after pregnancy/obesity
  • thinning hair

The benefits of filler therapy are based on two main approaches:

  • fast visual effect due to void filling
  • activation of inflammation, which causes reparative processes, including cell proliferation and de novo matrix formation

Despite the start of the skin remodeling process, fillers have certain disadvantages:

  • foreign substances (of animal origin or obtained by chemical synthesis) should be considered antigens
  • any kind of foreign material causes non-specific inflammation with cardiovascular reactions, edema and accumulation of leukocytes, secretion of cytokines and enzymes that cause destruction of the dermal matrix
  • in some cases, filler therapy is associated with the activation of dendritic cells, which trigger an immune response and can cause granuloma formation

Unlike filler therapy, PRP is a natural product and is 100% biocompatible! The absence of foreign antigens ensures that any complications are minimized. In addition, PRP stimulates the production of a tissue inhibitor of metalloproteinase (TIMP1), which limits the inflammatory response.

PRP-therapy provides a complete restoration of the chemical composition and architecture of the connective tissue due to the physiological stimulation of skin cells.

We answer the question: do you always need a targeted stimulation of regeneration and use of the potential of stem cells?

It is important to remember that the number of stem cells is limited. Although the body contains an excess supply of them, one should not tempt fate and uncontrollably use such a supply.

In addition, it is important to remember the Hayflick phenomenon. According to him, for each cell there is a limited number of divisions. A set of aesthetic problems for which patients seek professional help can be solved at a lower cost, using adequate body resources.

Therefore, it is important to choose the most appropriate treatment, taking into account the age, current condition of the skin, body and needs of the patient. Sometimes, to achieve the desired result, it is possible to improve microcirculation and cell trophism without sources of stem cells and stimulation of proliferative processes. For minimal age-related changes and preventive action, the use of autoplasma is sufficient. When signs of aging of cells and tissues appear, PRP therapy should be used.

PRF therapy is quite compatible with other therapies and procedures.

  • plasma therapy and PRP-therapy
  • biorevitalization with hyaluronic acid
  • mesotherapy

preparation for the procedure

0 min

duration of treatment

60 min

result

after 2 weeks

repeating procedure

4-6 months

Standard Skin Therapy aimed at improving skin tone, density and skin quality. Prevention of aging. It can also be prescribed before botulotherapy and surgery.
  • we recommend 6 separate consecutive treatments with an interval of 1 month
  • without rehabilitation
  • pain scale 4/10
  • satisfaction scale 10/10

Standard neck skin therapy aimed at working with transverse neck wrinkles, skin laxity and improving skin condition. Prevention of aging. It can also be prescribed before botulotherapy and surgery.

  • we recommend 2 separate treatments following each other with an interval of 1 month
  • the rehabilitation period is 5-7 days (may include micro-crises from piercing)
  • pain scale 5/10
  • satisfaction scale 10/10
Standard neck skin therapy aimed at working with transverse neck wrinkles, skin laxity and improving skin condition. Prevention of aging.
  • we recommend 2 separate treatments following each other with an interval of 1 month
  • the rehabilitation period is 5-7 days (may include micro-crises from piercing)
  • pain scale 5/10
  • satisfaction scale 10/10
Standard therapy for the area around the eyes for dark circles, nasolacrimal grooves, sagging eyelids, wrinkles. can be prescribed as a preparation for botulotherapy with a short duration of botulotherapy, as well as as a preparation for instrumental and surgical blepharoplasty Prevention of aging.
  • we recommend 2 separate treatments following each other with an interval of 1 month
  • the rehabilitation period is 5-7 days (may include micro-crises from piercing)
  • pain scale 4/10
  • satisfaction scale 10/10
Standard therapy for the area around the lips (purse lines), restoring color, moisturizing and restoring the natural relief of the lips. It can be prescribed in complex therapy as a contouring product to correct asymmetry and increase volume. Prevention of aging.
  • we recommend 2 separate treatments following each other with an interval of 1 month
  • the rehabilitation period is 5-7 days (may include micro-crises from piercing)
  • pain scale 6/10
  • satisfaction scale 10/10
Standard hair loss treatment, including hair loss and stress, to reduce the rate of hair loss and the number of hairs shed, as well as to accelerate new hair growth. It is prescribed to increase the density of brittle hair, improve its structure, quality and shine. Can be prescribed for scalp problems (oiliness, dandruff, itching).
  • we recommend 6 separate consecutive treatments with an interval of 1 month
  • without rehabilitation
  • pain scale 3/10
  • satisfaction scale 8/10

A standard therapy for aging hand skin to even out photoaging skin tone, thicken skin and improve the appearance of hands.

  • we recommend 2 separate treatments following each other with an interval of 1 month
  • without rehabilitation
  • pain scale 2/10
  • satisfaction scale 9/10
Standard treatment for earlobe sagging, volume reduction and stretched piercings. It is prescribed to increase the density of the lobe, improve the aesthetic appearance and improve the quality of the skin of the earlobe.
  • we recommend 2 separate treatments following each other with an interval of 1 month
  • without rehabilitation
  • pain scale 2/10
  • satisfaction scale 10/10

Auxiliary treatment of acne and acne scars. It is prescribed to reduce inflammation, improve the quality of the skin, improve the appearance of acne scars, stagnant spots and a prominent vascular network.

  • we recommend 4 separate consecutive treatments with an interval of 1 month
  • the rehabilitation period is 5-7 days (may include micro-crises from piercing)
Muscle relaxation therapy in the state of hypertonicity associated with the state of the teeth, habitual tension, orthodontic treatment (braces, implants, crowns), migraines, bruxism. It is prescribed to reduce the intensity of muscle tension, eliminate pain, increase oxygenation and blood flow to muscles and skin, reduce swelling and blood flow to the face.
  • we recommend 2 separate treatments following each other with an interval of 1 month
  • no rehabilitation (little pain in pain scale 4/10
  • satisfaction scale 10/10

Therapy of work with the lymphatic drainage system of the face and swellings associated with lifestyle, excess weight, hyaluronic acid injections. The therapy is aimed at eliminating edema, improving the appearance of the skin and facial contours. It can also be prescribed as rehabilitation after facelift surgery to reduce rehabilitation time.

  • we recommend 4 separate consecutive treatments with an interval of 1 month
  • the rehabilitation period is 5-7 days (may include microbruises after injections and slight swelling due to the activation of the lymphatic drainage system, small rashes)
  • pain scale 4/10
  • satisfaction scale 9/10

Therapy of post-traumatic and postoperative scars, stretch marks. The therapy is aimed at reducing pain, improving the appearance of the scar with a change in its color, density and extensibility.

  • we recommend 4 separate consecutive treatments with an interval of 1 month
  • the rehabilitation period is 5-7 days (may include microhematomas at the incision sites, slight swelling and soreness)
  • pain scale 5/10
  • satisfaction scale 8/10

Treatment of pain, including tension headaches, joints, back, neck. The therapy is aimed at alleviating pain, especially chronic pain, postoperative and post-traumatic pain, which affect the quality of sleep and life, social reputation and performance.

  • we recommend 1 treatment or therapy in an individual volume determined on the basis of a consultation
  • no rehabilitation (a little pain at the injection site the next day)
  • pain scale 5/10
  • satisfaction scale 9/10

Intellectual therapy of the musculo-fascial framework of the face to preserve youth and beauty, the therapy is aimed at preventing the appearance of “tired face”, “flyaways”, pastositis, nasolabial folds and “bags under the eyes”.

  • beginning of therapy: we recommend 2 separate treatments with an interval of a week, then 1 treatment every 2 months
  • no rehabilitation (a little pain at the injection site the next day)
  • pain scale 4/10
  • satisfaction scale 9/10

An intellectual therapy of immediate action, the procedure is aimed at rejuvenation at the target points of aging, in one procedure the techniques of influencing the most effective biologically active points of youth are combined, the stimulation of which leads to the activation of collagen synthesis, detoxification and a significant lifting effect. The ideal “Pre Party” procedure.

  • single WoW therapy: we recommend 5 separate treatments every 7, 14, 21, 28 and 35 days
  • no rehabilitation (a little pain at the injection site the next day)
  • pain scale 5/10
  • satisfaction scale 10/10

Intellectual therapy aimed at restoring sleep quality, reducing anxiety and chronic fatigue syndrome. Along with food and exercise, sleep is one of the three basic physiological needs of the body. And this means that without a sufficient amount of quality sleep, a person cannot be healthy – the human body will not be able to function properly. The therapy is prescribed to create healthy sleeping habits, reduce the number of night awakenings, fight against insomnia and the ability of the body to heal itself.

  • we recommend 4 separate consecutive treatments with an interval of 1 month
  • without rehabilitation
  • pain scale 4/10
  • satisfaction scale 9/10

Intellectual therapy aimed at reducing appetite and controlling body volume. The therapy helps reduce the feeling of hunger, makes it easier to follow a diet and avoid overeating in the evening. During therapy, healthy habits are formed, such as eating smaller portions of food, the absence of uncontrolled hunger pangs, restoring a healthy drinking regime, in addition to reducing appetite, the protocol also helps to change eating habits – reduce cravings for sweets and starchy foods

  • 165 / 5 000 Výsledky prekladov Výsledok prekladu star_border we recommend 4 separate consecutive treatments with an interval of 1 month. An agreement on the date of the procedure (day of the menstrual cycle for women) is required.
  • without rehabilitation
  • pain scale 6/10
  • satisfaction scale 9/10

Intelligent therapy to reduce the symptoms of excessive use of hyaluronic acid fillers and symptoms of “very tired face”, persistent swelling, sagging skin, gray skin, enlarged pores. Therapy helps restore oxygenation and normal blood circulation, reduce morning swelling, restore skin elasticity, relief and tone. The perfect “After Party” treatment

  • we recommend 4 consecutive treatments every 7, 14, 14, 7 days
  • the rehabilitation period is 5-7 days (may include microbruises after injections and slight swelling due to the activation of the lymphatic drainage system, small rashes)
  • pain scale 5/10
  • satisfaction scale 10/10

Intellectual therapy to restore the low level of enjoyment of life associated with back and limb pain. It stabilizes the psycho-emotional background, increases the level of satisfaction with life, relieves pain and gives lightness to the body.

  • we recommend 6 separate consecutive treatments with an interval of 1 month
  • without rehabilitation
  • pain scale 6/10
  • satisfaction scale 9/10

Luxurious therapy for the most effective preservation of health and beauty. The therapy includes several levels of layered facial restoration at all levels and is a powerful tool for preventing bone resorption, strengthening ligaments, restoring muscles and fat compartments of the face, maintaining and improving skin quality. The preventive 12-step anti-aging face lifting procedure allows you to get the effect of plastic surgery. The procedure stimulates the elimination of toxins, smoothes wrinkles and gives the skin a healthy tone and luxurious brightness.

  • preventive therapy consists of 6 separate treatments per year
  • recovery period 2-3 days (may include micro-bruising after the puncture and slight swelling)
  • pain scale 5/10
  • satisfaction scale 10/10

Procedure for preparing blood plasma for PRP therapy

blood sampling from a peripheral vein

Whole blood is collected from a peripheral vein using a venipuncture kit into tubes containing an anticoagulant. The ratio between the obtained PRP and blood is 1:4.5 (which can be interpreted as obtaining 2 ml of PRP from 9 ml of whole blood).

centrifugation

To carry out this procedure, you will need a device – a centrifuge. The centrifugation process separates the cell layers based on cell mass. The tubes will be placed opposite each other in the rotating head of the centrifuge to achieve balance. The most important thing when spinning is to reach 1500G in 8 minutes to achieve favorable results. If the centrifugation was successful, 3 layers can be seen in the tube.

collection of PRP (Platelet Rich Plasma)

A long needle is attached to the syringe and this device is inserted vertically into the tube at the edge of the tube, exactly to the edge of the leukocyte border. The collection is carried out by rotating the needle.

re-suspension process

PRP is collected from several centrifuged tubes into one resuspension tube. The resuspension tube should be shaken gently for 30 seconds to 1 minute to prevent cell clumping. This procedure promotes cell homogenization in the plasma medium. The resuspension tube is suitable for plasma activation when plasma is mixed with calcium chloride. Activated plasma has a stronger regenerative effect.

PRP submission

Plasma is applied by local injection into the treated area. Platelets together with their growth factors (PDGF AB and BB, IGF, EFG, VEGF, TGF Beta 1 and Beta 2) activate a cascade of anti-inflammatory, regenerative and reparative processes in pathologically altered tissues, especially tendons, cartilage, skin and bones, stimulate wound healing or skin imperfections, giving the skin a lifting effect.

collection of PRP (Platelet Rich Plasma)

A long needle is attached to the syringe and this device is inserted vertically into the tube at the edge of the tube, exactly to the edge of the leukocyte border. The collection is carried out by rotating the needle. It is recommended to collect a small amount of red blood cells along with white plaque on red blood cells, which is due to intercellular interactions during the resuspension process.

1.

non-platelet rich plasma

2.

rich in trombocytes plasma

3.

leukocyte coating

4.

erythrocytes

interpretation of in vitro layers

A layer of erythrocytes forms at the bottom of the tube, since erythrocytes are the largest cells. Directly above the layer of erythrocytes is a thin layer of leukocytes, which has a specific white color. The top layer is yellowish. This layer contains platelet-rich plasma (PRP) at the bottom and freely transitions to non-platelet-rich plasma (PPP) at the top.

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